A new Pilot Project Program is now available to support projects in GI cancer-related research. A total of $140,000 will be available, sufficient for funding two to three grants at $45-$70,000 per annum for one to two years to each successful applicant. Priority will be given to translational research projects, though basic research that has obvious applications in the near-term will also be considered. Novelty and applicability are particularly important. Funds for this new pilot project program are being provided by the GI SPORE grants. Please note that that there will be no other solicitations for pilot projects for the GI Grant. Grants must be submitted electronically through a simple web form, available at: http://oncweb1-vm.onc.jhmi.edu/pilotprojects/ Plans that are longer than two pages will be discarded. A Biosketch with Other Support is required. No budget is required. All entries must be completed by June 3, 2013 at 5:00 PM. Selections of grants for funding will be made shortly thereafter. The funding period will be July 1, 2013 – June 30, 2014. Sincerely, Bert Vogelstein Program Leader, GI SPORE Developmental Projects and Scott Kern Director, GI SPORE

Funding up to $125,000 direct costs per investigator at each institution. Letters of Intent (Partner Identified) and Letters of Interest (Searching for Partner) are due by August 2, 2012. LOIs are requested so that advice and assistance can be provided to identify partners and prepare the application. Full proposals will be due by September 4, 2012. A complete PHS 398 application is required by the NCI partnership guidelines.

Funding up to $60,000 direct costs per investigator at each institution. Awards will be made for pilot projects or feasibility studies preparatory to the development of an application for independent peer-reviewed support. Letters of Intent (Partner Identified) and Letters of Interest (Searching for Partner) are due by August 2, 2012. LOIs are requested so that advice and assistance can be provided to identify partners and prepare the application. Application guidelines and forms follow. Proposals are due September 4, 2012.